A comparative analysis of computational approaches to relative protein quantification using peptide peak intensities in label-free LC-MS proteomics experiments

Liquid chromatography coupled with mass spectrometry (LC-MS) is widely used to identify and quantify peptides in complex biological samples. In particular, label-free shotgun proteomics is highly effective for the identification of peptides and subsequently obtaining a global protein profile of a sa...

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Detalhes bibliográficos
Main Authors: Matzke, Melissa M., Brown, Joseph N., Gritsenko, Marina A., Metz, Thomas O., Pounds, Joel G., Rodland, Karin D., Shukla, Anil K., Smith, Richard D., Waters, Katrina M., McDermott, Jason E., Webb-Robertson, Bobbie-Jo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775642/
https://ncbi.nlm.nih.gov/pubmed/23019139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201200269
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