ADAM10 Expression and Promoter Haplotype in Alzheimer’s Disease

Alzheimer’s disease is confirmed at autopsy according to the accumulation of brain neuritic plaques and neurofibrillary tangles in the brain. Neuritic plaques contain Aβ and lower levels of Aβ correspond to an increase in ADAM10 α-secretase activity. ADAM10 α-secretase activity produces a soluble AP...

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Bibliografiska uppgifter
Huvudupphovsmän: Bekris, L.M., Lutz, F., Li, G., Galasko, D.R., Farlow, M.R., Quinn, J.F., Kaye, J.A., Leverenz, J.B., Tsuang, D.W., Montine, T.J., Peskind, E.R., Yu, C.E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391324/
https://ncbi.nlm.nih.gov/pubmed/22572541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.03.013
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