Protection of Blood Retinal Barrier and Systemic Vasculature by Insulin-Like Growth Factor Binding Protein-3

Previously, we showed that insulin growth factor (IGF)-1 binding protein-3 (IGFBP-3), independent of IGF-1, reduces pathological angiogenesis in a mouse model of the oxygen-induced retinopathy (OIR). The current study evaluates novel endothelium-dependent functions of IGFBP-3 including blood retinal...

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Detalhes bibliográficos
Principais autores: Jarajapu, Yagna P. R., Cai, Jun, Yan, Yuanqing, Li Calzi, Sergio, Kielczewski, Jennifer L., Hu, Ping, Shaw, Lynn C., Firth, Sue M., Chan-Ling, Tailoi, Boulton, Michael E., Baxter, Robert C., Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391198/
https://ncbi.nlm.nih.gov/pubmed/22792172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039398
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