Homeostatic Synaptic Scaling Is Regulated by Protein SUMOylation

Homeostatic scaling allows neurons to alter synaptic transmission to compensate for changes in network activity. Here, we show that suppression of network activity with tetrodotoxin, which increases surface expression of AMPA receptors (AMPARs), dramatically reduces levels of the deSUMOylating (wher...

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Bibliografski detalji
Glavni autori: Craig, Tim J., Jaafari, Nadia, Petrovic, Milos M., Rubin, Philip P., Mellor, Jack R., Henley, Jeremy M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Neurobiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391081/
https://ncbi.nlm.nih.gov/pubmed/22582390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356337
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