Heparan Sulfate Facilitates FGF and BMP Signaling to Drive Mesoderm Differentiation of Mouse Embryonic Stem Cells

Heparan sulfate (HS) has been implicated in regulating cell fate decisions during differentiation of embryonic stem cells (ESCs) into advanced cell types. However, the necessity and the underlying molecular mechanisms of HS in early cell lineage differentiation are still largely unknown. In this stu...

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Bibliografiska uppgifter
Huvudupphovsmän: Kraushaar, Daniel C., Rai, Sumit, Condac, Eduard, Nairn, Alison, Zhang, Siyuan, Yamaguchi, Yu, Moremen, Kelley, Dalton, Stephen, Wang, Lianchun
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
Ämnen:
Glycobiology and Extracellular Matrices
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391080/
https://ncbi.nlm.nih.gov/pubmed/22556407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.368241
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