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Depletion of Tregs for adoptive T-cell therapy using CD44 and CD137 as selection markers

Several types of cancer have been shown to be susceptible to cellular immune responses, leading to investigations using various forms of T cell-based, tumor-directed immunotherapy. One potential obstacle for the successful application of these therapies is the suppressive function of Tregs. Goldstei...

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Autors principals: Till, Brian G, Press, Oliver W
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390965/
https://ncbi.nlm.nih.gov/pubmed/22642331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.12.33
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