Ex vivo enrichment of PRAME antigen‐specific T cells for adoptive immunotherapy using CD137 activation marker selection

OBJECTIVE: Adoptive immunotherapy with ex vivo expanded tumor‐specific T cells has potential as anticancer therapy. Preferentially expressed antigen in melanoma (PRAME) is an attractive target overexpressed in several cancers including melanoma and acute myeloid leukaemia (AML), with low expression...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Lee, Koon H, Gowrishankar, Kavitha, Street, Janine, McGuire, Helen M, Luciani, Fabio, Hughes, Brendan, Singh, Mandeep, Clancy, Leighton E, Gottlieb, David J, Micklethwaite, Kenneth P, Blyth, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577233/
https://ncbi.nlm.nih.gov/pubmed/33101678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1200
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