Survivin is highly expressed in CD34(+)38(−) leukemic stem/progenitor cells and predicts poor clinical outcomes in AML

Survivin, a member of the inhibitors of apoptosis protein family, plays important roles in cell proliferation and survival and is highly expressed in various malignancies, including leukemias. To better understand its role in acute myeloid leukemia (AML), we profiled survivin expression in samples o...

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Bibliografiske detaljer
Main Authors: Carter, Bing Z., Qiu, Yihua, Huang, Xuelin, Diao, Lixia, Zhang, Nianxiang, Coombes, Kevin R., Mak, Duncan H., Konopleva, Marina, Cortes, Jorge, Kantarjian, Hagop M., Mills, Gordon B., Andreeff, Michael, Kornblau, Steven M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390955/
https://ncbi.nlm.nih.gov/pubmed/22645176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-409888
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