Survivin is highly expressed in CD34(+)38(−) leukemic stem/progenitor cells and predicts poor clinical outcomes in AML

Survivin, a member of the inhibitors of apoptosis protein family, plays important roles in cell proliferation and survival and is highly expressed in various malignancies, including leukemias. To better understand its role in acute myeloid leukemia (AML), we profiled survivin expression in samples o...

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Detalles Bibliográficos
Main Authors: Carter, Bing Z., Qiu, Yihua, Huang, Xuelin, Diao, Lixia, Zhang, Nianxiang, Coombes, Kevin R., Mak, Duncan H., Konopleva, Marina, Cortes, Jorge, Kantarjian, Hagop M., Mills, Gordon B., Andreeff, Michael, Kornblau, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2012
Assuntos:
Myeloid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390955/
https://ncbi.nlm.nih.gov/pubmed/22645176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-409888
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