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Modeling regionalized volumetric differences in protein-ligand binding cavities

Identifying elements of protein structures that create differences in protein-ligand binding specificity is an essential method for explaining the molecular mechanisms underlying preferential binding. In some cases, influential mechanisms can be visually identified by experts in structural biology,...

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Autors principals: Chen, Brian Y, Bandyopadhyay, Soutir
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390949/
https://ncbi.nlm.nih.gov/pubmed/22759583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-10-S1-S6
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