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VASP: A Volumetric Analysis of Surface Properties Yields Insights into Protein-Ligand Binding Specificity

Many algorithms that compare protein structures can reveal similarities that suggest related biological functions, even at great evolutionary distances. Proteins with related function often exhibit differences in binding specificity, but few algorithms identify structural variations that effect spec...

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Detalhes bibliográficos
Main Authors: Chen, Brian Y., Honig, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930297/
https://ncbi.nlm.nih.gov/pubmed/20814581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000881
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