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Ligand binding to proteins: the binding landscape model.

Models of ligand binding are often based on four assumptions: (1) steric fit: that binding is determined mainly by shape complementarity; (2) native binding: that ligands mainly bind to native states; (3) locality: that ligands perturb protein structures mainly at the binding site; and (4) continuit...

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Bibliographic Details
Main Authors: Miller, D. W., Dill, K. A.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143563/
https://ncbi.nlm.nih.gov/pubmed/9336839
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