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Antisense-mediated exon inclusion
Exon skipping induced by gene mutations is a common mechanism responsible for many genetic diseases. A practical approach to correct the aberrant splicing of defective genes is to use antisense oligonucleotides (ASOs). The recognition of splice sites and the regulation of splicing involve multiple p...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390937/ https://ncbi.nlm.nih.gov/pubmed/22454070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-767-5_20 |
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