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RNA therapeutics: Beyond RNA interference and antisense oligonucleotides
Here we discuss three RNA therapeutic technologies exploiting various oligonucleotides that bind RNA by base-pairing in a sequence-specific manner yet have different mechanisms of action and effects. RNA interference and antisense oligonucleotides downregulate gene expression by enzyme-dependent deg...
Gorde:
| Argitaratua izan da: | Nat Rev Drug Discov |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743652/ https://ncbi.nlm.nih.gov/pubmed/22262036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3625 |
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