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Antisense-mediated exon inclusion

Exon skipping induced by gene mutations is a common mechanism responsible for many genetic diseases. A practical approach to correct the aberrant splicing of defective genes is to use antisense oligonucleotides (ASOs). The recognition of splice sites and the regulation of splicing involve multiple p...

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Detalhes bibliográficos
Main Authors: Hua, Yimin, Krainer, Adrian R
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390937/
https://ncbi.nlm.nih.gov/pubmed/22454070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-767-5_20
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