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Zinc-finger nuclease-mediated targeted insertion of reporter genes for quantitative imaging of gene expression in sea urchin embryos

To understand complex biological systems, such as the development of multicellular organisms, it is important to characterize the gene expression dynamics. However, there is currently no universal technique for targeted insertion of reporter genes and quantitative imaging in multicellular model syst...

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Detalhes bibliográficos
Main Authors: Ochiai, Hiroshi, Sakamoto, Naoaki, Fujita, Kazumasa, Nishikawa, Masatoshi, Suzuki, Ken-ichi, Matsuura, Shinya, Miyamoto, Tatsuo, Sakuma, Tetsushi, Shibata, Tatsuo, Yamamoto, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390856/
https://ncbi.nlm.nih.gov/pubmed/22711830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202768109
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