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CRISPR-Cas9 editing of non-coding genomic loci as a means of controlling gene expression in the sea urchin
We seek to manipulate gene function here through CRISPR-Cas9 editing of cis-regulatory sequences, rather than the more typical mutation of coding regions. This approach would minimize secondary effects of cellular responses to nonsense mediated decay pathways or to mutant protein products by prematu...
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| Publicado no: | Dev Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7956150/ https://ncbi.nlm.nih.gov/pubmed/33482173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2021.01.003 |
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