Unexpected tautomeric equilibria of the carbanion-enamine intermediate in pyruvate oxidase highlight unrecognized chemical versatility of thiamin

Lignende værker

• Double Duty for a Conserved Glutamate in Pyruvate Decarboxylase: Evidence of the Participation in Stereoelectronically Controlled Decarboxylation and in Protonation of the Nascent Carbanion/Enamine Intermediate,
  af: Meyer, Danilo, et al.
  Udgivet: (2010)
• Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4′-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase
  af: Balakrishnan, Anand, et al.
  Udgivet: (2012)
• Tautomeric Equilibria of Nucleobases in the Hachimoji Expanded Genetic Alphabet
  af: Eberlein, Lukas, et al.
  Udgivet: (2020)
• Tautomeric and Microscopic Protonation Equilibria of Anthranilic Acid and Its Derivatives
  af: Zapała, Lidia, et al.
  Udgivet: (2014)
• Role of E166 in the imine to enamine tautomerization of the clinical β-lactamase inhibitor sulbactam
  af: Kalp, Matthew, et al.
  Udgivet: (2009)