Tautomeric Equilibria of Nucleobases in the Hachimoji Expanded Genetic Alphabet

Evolution has yielded biopolymers that are constructed from exactly four building blocks and are able to support Darwinian evolution. Synthetic biology aims to extend this alphabet, and we recently showed that 8-letter (hachimoji) DNA can support rule-based information encoding. One source of replic...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Eberlein, Lukas, Beierlein, Frank R., Hommes, Nico J. R. van Eikema, Radadiya, Ashish, Heil, Jochen, Benner, Steven A., Clark, Timothy, Kast, Stefan M., Richards, Nigel G. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549732/
https://ncbi.nlm.nih.gov/pubmed/32125859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.9b01079
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