Tautomeric Equilibria of Nucleobases in the Hachimoji Expanded Genetic Alphabet

Evolution has yielded biopolymers that are constructed from exactly four building blocks and are able to support Darwinian evolution. Synthetic biology aims to extend this alphabet, and we recently showed that 8-letter (hachimoji) DNA can support rule-based information encoding. One source of replic...

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Библиографические подробности
Опубликовано в: :J Chem Theory Comput
Главные авторы: Eberlein, Lukas, Beierlein, Frank R., Hommes, Nico J. R. van Eikema, Radadiya, Ashish, Heil, Jochen, Benner, Steven A., Clark, Timothy, Kast, Stefan M., Richards, Nigel G. J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549732/
https://ncbi.nlm.nih.gov/pubmed/32125859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.9b01079
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