Tautomeric Equilibria of Nucleobases in the Hachimoji Expanded Genetic Alphabet

Evolution has yielded biopolymers that are constructed from exactly four building blocks and are able to support Darwinian evolution. Synthetic biology aims to extend this alphabet, and we recently showed that 8-letter (hachimoji) DNA can support rule-based information encoding. One source of replic...

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Pubblicato in:J Chem Theory Comput
Autori principali: Eberlein, Lukas, Beierlein, Frank R., Hommes, Nico J. R. van Eikema, Radadiya, Ashish, Heil, Jochen, Benner, Steven A., Clark, Timothy, Kast, Stefan M., Richards, Nigel G. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549732/
https://ncbi.nlm.nih.gov/pubmed/32125859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.9b01079
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