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Emerging beneficial roles of sirtuins in heart failure
Sirtuins are a highly conserved family of histone/protein deacetylases whose activity can prolong the lifespan of model organisms such as yeast, worms and flies. In mammalian cells, seven sirtuins (SIRT1–7) modulate distinct metabolic and stress-response pathways, SIRT1 and SIRT3 having been most ex...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer-Verlag
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390697/ https://ncbi.nlm.nih.gov/pubmed/22622703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-012-0273-5 |
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