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Nigericin-induced Impairment of Autophagic Flux in Neuronal Cells Is Inhibited by Overexpression of Bak

Bak is a prototypic pro-apoptotic Bcl-2 family protein expressed in a wide variety of tissues and cells. Recent studies have revealed that Bcl-2 family proteins regulate apoptosis as well as autophagy. To investigate whether and how Bak exerts a regulatory role on autophagy-related events, we treate...

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Detalhes bibliográficos
Main Authors: Lim, Junghyun, Lee, Yunsu, Kim, Hyun-Wook, Rhyu, Im Joo, Oh, Myung Sook, Youdim, Moussa B. H., Yue, Zhenyu, Oh, Young J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390606/
https://ncbi.nlm.nih.gov/pubmed/22493436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364281
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