Importance of SPP1 genotype as a covariate in clinical trials in Duchenne muscular dystrophy

OBJECTIVE: To test the effect of the single nucleotide polymorphism −66 T>G (rs28357094) in the osteopontin gene (SPP1) on functional measures over 12 months in Duchenne muscular dystrophy (DMD). METHODS: This study was conducted on a cohort of ambulatory patients with DMD from a network of Itali...

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Hlavní autoři: Bello, Luca, Piva, Luisa, Barp, Andrea, Taglia, Antonella, Picillo, Esther, Vasco, Gessica, Pane, Marika, Previtali, Stefano C., Torrente, Yvan, Gazzerro, Elisabetta, Chiara Motta, Maria, Grieco, Gaetano S., Napolitano, Sara, Magri, Francesca, D'Amico, Adele, Astrea, Guja, Messina, Sonia, Sframeli, Maria, Luca Vita, Gian, Boffi, Patrizia, Mongini, Tiziana, Ferlini, Alessandra, Gualandi, Francesca, Soraru', Gianni, Ermani, Mario, Vita, Giuseppe, Battini, Roberta, Bertini, Enrico, Comi, Giacomo P., Berardinelli, Angela, Minetti, Carlo, Bruno, Claudio, Mercuri, Eugenio, Politano, Luisa, Angelini, Corrado, Hoffman, Eric P., Pegoraro, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390537/
https://ncbi.nlm.nih.gov/pubmed/22744661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e31825f04ea
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