Importance of SPP1 genotype as a covariate in clinical trials in Duchenne muscular dystrophy

OBJECTIVE: To test the effect of the single nucleotide polymorphism −66 T>G (rs28357094) in the osteopontin gene (SPP1) on functional measures over 12 months in Duchenne muscular dystrophy (DMD). METHODS: This study was conducted on a cohort of ambulatory patients with DMD from a network of Itali...

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Main Authors: Bello, Luca, Piva, Luisa, Barp, Andrea, Taglia, Antonella, Picillo, Esther, Vasco, Gessica, Pane, Marika, Previtali, Stefano C., Torrente, Yvan, Gazzerro, Elisabetta, Chiara Motta, Maria, Grieco, Gaetano S., Napolitano, Sara, Magri, Francesca, D'Amico, Adele, Astrea, Guja, Messina, Sonia, Sframeli, Maria, Luca Vita, Gian, Boffi, Patrizia, Mongini, Tiziana, Ferlini, Alessandra, Gualandi, Francesca, Soraru', Gianni, Ermani, Mario, Vita, Giuseppe, Battini, Roberta, Bertini, Enrico, Comi, Giacomo P., Berardinelli, Angela, Minetti, Carlo, Bruno, Claudio, Mercuri, Eugenio, Politano, Luisa, Angelini, Corrado, Hoffman, Eric P., Pegoraro, Elena
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390537/
https://ncbi.nlm.nih.gov/pubmed/22744661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e31825f04ea
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