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Loss of the Integrin-Activating Transmembrane Protein Fam38A (Piezo1) Promotes a Switch to a Reduced Integrin-Dependent Mode of Cell Migration

Lung cancer is one of the most common fatal diseases in the developed world. The disease is rarely cured by currently available therapies, with an overall survival rate of ∼10%. Characterizing novel proteins that offer crucial insights into the processes of lung tumour invasion and metastasis may th...

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Main Authors: McHugh, Brian J., Murdoch, Amanda, Haslett, Christopher, Sethi, Tariq
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390408/
https://ncbi.nlm.nih.gov/pubmed/22792288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040346
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