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Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum

The integrin family of heterodimeric cell-surface receptors are fundamental in cell-cell and cell-matrix adhesion. Changes to either integrin-ligand affinity or integrin gene expression are central to a variety of disease processes, including inflammation, cardiovascular disease and cancer. In scree...

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Библиографические подробности
Главные авторы: McHugh, Brian J., Buttery, Robert, Lad, Yatish, Banks, Stephen, Haslett, Christopher, Sethi, Tariq
Формат: Artigo
Язык:Inglês
Опубликовано: Company of Biologists 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794710/
https://ncbi.nlm.nih.gov/pubmed/20016066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.056424
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