Quantitative Analysis of Survivin Protein Expression and Its Therapeutic Depletion by an Antisense Oligonucleotide in Human Lung Tumors

RNA-directed antisense and interference therapeutics are a promising treatment option for cancer. The demonstration of depletion of target proteins within human tumors in vivo using validated methodology will be a key to the application of this technology. Here, we present a flow cytometric-based ap...

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Библиографические подробности
Главные авторы: Olsen, Anna L, Davies, Joanne M, Medley, Louise, Breen, David, Talbot, Denis C, McHugh, Peter J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2012
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390226/
https://ncbi.nlm.nih.gov/pubmed/23344082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.19
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