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Hydrogen exchange mass spectrometry: Are we out of the quicksand?

Although the use of hydrogen exchange (HX) mass spectrometry (MS) to study proteins and protein conformation is now over 20 years old, the perception lingers that it still has “issues”. Is this method, in fact, still in the quicksand with many remaining obstacles to overcome? We do not think so. Thi...

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Autors principals: Iacob, Roxana E., Engen, John R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389995/
https://ncbi.nlm.nih.gov/pubmed/22476891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-012-0377-z
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