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Improved Models for Transcription Factor Binding Site Identification Using Nonindependent Interactions
Identifying transcription factor (TF) binding sites is essential for understanding regulatory networks. The specificity of most TFs is currently modeled using position weight matrices (PWMs) that assume the positions within a binding site contribute independently to binding affinity for any site. Ex...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Genetics Society of America
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389974/ https://ncbi.nlm.nih.gov/pubmed/22505627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.138685 |
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