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Inferring Binding Energies from Selected Binding Sites
We employ a biophysical model that accounts for the non-linear relationship between binding energy and the statistics of selected binding sites. The model includes the chemical potential of the transcription factor, non-specific binding affinity of the protein for DNA, as well as sequence-specific p...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777355/ https://ncbi.nlm.nih.gov/pubmed/19997485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000590 |
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