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Zinc Thiolate Reactivity toward Nitrogen Oxides: Insights into the Interaction of Zn(2+) with S-Nitrosothiols and Implications for Nitric Oxide Synthase

Zinc thiolate complexes containing N(2)S tridentate ligands were prepared to investigate their reactivity toward reactive nitrogen species, chemistry proposed to occur at the zinc tetracysteine thiolate site of nitric oxide synthase (NOS). The complexes are unreactive toward nitric oxide in the abse...

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Detalhes bibliográficos
Main Authors: Kozhukh, Julia, Lippard, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389809/
https://ncbi.nlm.nih.gov/pubmed/22702952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic3007684
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