Phase 1 Dose- Escalation Trial of Clofarabine Followed by Escalating Dose of Fractionated Cyclophosphamide in Adults with Relapsed or Refractory Acute Leukaemias

The prognosis of patients with relapsed and refractory acute leukaemia (RRAL) is very poor. Forty patients with RRAL were enrolled (28 acute myeloid leukaemia [AML], 12 acute lymphoblastic leukaemia [ALL]) in this Phase 1 dose-escalation trial of daily-infused clofarabine (CLO) followed by cyclophos...

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Detalhes bibliográficos
Main Authors: Zeidan, Amer M, Ricklis, Rebecca M, Carraway, Hetty E, Yun, Hyun D, Greer, Jacqueline M, Smith, B Douglas, Levis, Mark J, McDevitt, Michael A, Pratz, Keith W, Showel, Margaret M, Gladstone, Douglas E, Gore, Steven D, Karp, Judith E
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389586/
https://ncbi.nlm.nih.gov/pubmed/22594769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2012.09142.x
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