A phase 1 clinical-laboratory study of clofarabine followed by cyclophosphamide for adults with refractory acute leukemias

Clofarabine has shown impressive response rates in patients with acute leukemias. In vitro investigations with clofarabine in combination with cyclophosphamide in primary cells have demonstrated synergistic cytotoxicity and inhibition of DNA repair. Based on these clinical and laboratory observation...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Karp, Judith E., Ricklis, Rebecca M., Balakrishnan, Kumudha, Briel, Janet, Greer, Jacqueline, Gore, Steven D., Smith, B. Douglas, McDevitt, Michael A., Carraway, Hetty, Levis, Mark J., Gandhi, Varsha
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2007
Aiheet:
Clinical Trials and Observations
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976362/
https://ncbi.nlm.nih.gov/pubmed/17562873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-081364
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