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Rapid Chemoselective Bioconjugation Through the Oxidative Coupling of Anilines and Aminophenols
A highly efficient protein bioconjugation method is described involving the addition of anilines to o-aminophenols in the presence of sodium periodate. The reaction takes place in aqueous buffer at pH 6.5 and can reach high levels of completion in 2–5 min. The product of the reaction has been charac...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389565/ https://ncbi.nlm.nih.gov/pubmed/21919497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2033298 |
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