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Distal CCAAT box deletion in the A gamma globin gene of two black adolescents with elevated fetal A gamma globin.

Point mutations in G gamma and A gamma globin gene promoters are associated with increased production of G gamma and A gamma globin, respectively. To determine whether an upstream promoter mutation could account for elevated A gamma in a Black adolescent with A gamma-beta+-HPFH and sickle cell trait...

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Main Authors: Gilman, J G, Mishima, N, Wen, X J, Stoming, T A, Lobel, J, Huisman, T H
Format: Artigo
Jezik:Inglês
Izdano: 1988
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC338929/
https://ncbi.nlm.nih.gov/pubmed/2462713
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