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The effects of HPFH mutations in the human gamma-globin promoter on binding of ubiquitous and erythroid specific nuclear factors.
Genetic evidence indicates that single point mutations in the gamma-globin promoter may be the cause of high expression of the mutated gene in the adult period (Hereditary Persistence of Fetal Hemoglobin, HPFH). Here we show that one of these mutations characterized by a T----C substitution at posit...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1988
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338490/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2458563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.16.7783 |
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