Assay and Inhibition of Diacylglycerol Lipase Activity

A series of N-formyl-α-amino acid esters of β-lactone derivatives structurally related to tetrahydrolipstatin (THL) and O-3841 were synthesized that inhibit human and murine diacylglycerol lipase (DAGL) activities. New ether lipid reporter compounds were developed for an in vitro assay to efficientl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Johnston, Meghan, Bhatt, Shachi R., Sikka, Surina, Mercier, Richard W., West, Jay M., Makriyannis, Alexandros, Gatley, S. John, Duclos, Richard I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389199/
https://ncbi.nlm.nih.gov/pubmed/22738638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.05.101
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