Assay and Inhibition of Diacylglycerol Lipase Activity

A series of N-formyl-α-amino acid esters of β-lactone derivatives structurally related to tetrahydrolipstatin (THL) and O-3841 were synthesized that inhibit human and murine diacylglycerol lipase (DAGL) activities. New ether lipid reporter compounds were developed for an in vitro assay to efficientl...

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Detaylı Bibliyografya
Asıl Yazarlar: Johnston, Meghan, Bhatt, Shachi R., Sikka, Surina, Mercier, Richard W., West, Jay M., Makriyannis, Alexandros, Gatley, S. John, Duclos, Richard I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389199/
https://ncbi.nlm.nih.gov/pubmed/22738638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.05.101
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