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Assay and Inhibition of Diacylglycerol Lipase Activity
A series of N-formyl-α-amino acid esters of β-lactone derivatives structurally related to tetrahydrolipstatin (THL) and O-3841 were synthesized that inhibit human and murine diacylglycerol lipase (DAGL) activities. New ether lipid reporter compounds were developed for an in vitro assay to efficientl...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389199/ https://ncbi.nlm.nih.gov/pubmed/22738638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.05.101 |
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