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Microarray-based gene expression profiling reveals the mediators and pathways involved in the anti-arthritic activity of Celastrus-derived Celastrol

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints. The prolonged use of anti-inflammatory drugs and other newer drugs is associated with severe adverse reactions. Therefore, there is a need for newer anti-arthritic agents. Celastrol, a bioactive c...

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Autors principals: Yu, Hua, Venkatesha, Shivaprasad H., Moudgil, Kamal D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389174/
https://ncbi.nlm.nih.gov/pubmed/22664142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2012.05.015
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