Identification of functional domains of the IR2 protein of equine herpesvirus 1 required for inhibition of viral gene expression and replication

The equine herpesvirus 1 (EHV-1) negative regulatory IR2 protein (IR2P), an early 1,165-amino acid (aa) truncated form of the 1,487-aa immediate-early protein (IEP), lacks the trans-activation domain essential for IEP activation functions but retains domains for binding DNA, TFIIB, and TBP and the n...

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Hlavní autoři: Kim, Seong K., Kim, Seongman, Dai, Gan, Zhang, Yunfei, Ahn, Byung C., O'Callaghan, Dennis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388945/
https://ncbi.nlm.nih.gov/pubmed/21794889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.06.023
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