The Unique IR2 Protein of Equine Herpesvirus 1 Negatively Regulates Viral Gene Expression

The IR2 protein (IR2P) is a truncated form of the immediate-early protein (IEP) lacking the essential acidic transcriptional activation domain (TAD) and serine-rich tract and yet retaining binding domains for DNA and TFIIB and nuclear localization signal (NLS). Analysis of the IR2 promoter indicated...

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Autores principales: Kim, Seong K., Ahn, Byung C., Albrecht, Randy A., O'Callaghan, Dennis J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472049/
https://ncbi.nlm.nih.gov/pubmed/16641295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.10.5041-5049.2006
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