The UL4 protein of equine herpesvirus 1 is not essential for replication or pathogenesis and inhibits gene expression controlled by viral and heterologous promoters

Defective interfering particles (DIP) of equine herpesvirus 1 (EHV-1) inhibit standard virus replication and mediate persistent infection. The DIP genome is comprised of only three genes: UL3, UL4, and a hybrid gene composed of portions of the IR4 (EICP22) and UL5 (EICP27) genes. The hybrid gene is...

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Hlavní autoři: Charvat, Robert A., Breitenbach, Jonathan E., Ahn, ByungChul, Zhang, Yunfei, O’Callaghan, Dennis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060994/
https://ncbi.nlm.nih.gov/pubmed/21324502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.01.025
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