Deletion of the UL4 gene sequence of equine herpesvirus 1 precludes the generation of defective interfering particles

Serial, high multiplicity passage of equine herpesvirus 1 (EHV-1) leads to the generation of defective interfering particles (DIP). EHV-1 DIP inhibit and interfere with the replication of standard EHV-1, establishing a state of persistent infection. These DIP package severely truncated and rearrange...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Charvat, Robert A., Zhang, Yunfei, O’Callaghan, Dennis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595000/
https://ncbi.nlm.nih.gov/pubmed/22752566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11262-012-0781-2
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky