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Deletion of the UL4 gene sequence of equine herpesvirus 1 precludes the generation of defective interfering particles
Serial, high multiplicity passage of equine herpesvirus 1 (EHV-1) leads to the generation of defective interfering particles (DIP). EHV-1 DIP inhibit and interfere with the replication of standard EHV-1, establishing a state of persistent infection. These DIP package severely truncated and rearrange...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595000/ https://ncbi.nlm.nih.gov/pubmed/22752566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11262-012-0781-2 |
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