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Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity
Post-translational protein phosphorylation by protein kinase A (PKA) is a ubiquitous signalling mechanism which regulates many cellular processes. A low-temperature X-ray structure of the ternary complex of the PKA catalytic subunit (PKAc) with ATP and a 20-residue peptidic inhibitor (IP20) at the p...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388813/ https://ncbi.nlm.nih.gov/pubmed/22751671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444912014886 |
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