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Replication-Deficient Rabies Virus–Based Vaccines Are Safe and Immunogenic in Mice and Nonhuman Primates

Although current postexposure prophylaxis rabies virus (RV) vaccines are effective, ~40,000–70,000 rabies-related deaths are reported annually worldwide. The development of effective formulations requiring only 1–2 applications would significantly reduce mortality. We assessed in mice and nonhuman p...

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Detalhes bibliográficos
Main Authors: Cenna, Jonathan, Hunter, Meredith, Tan, Gene S., Papaneri, Amy B., Ribka, Erin P., Schnell, Matthias J., Marx, Preston A., McGettigan, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388800/
https://ncbi.nlm.nih.gov/pubmed/19764884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/605949
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