HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability

Expression and cellular distribution of claudin-1, a tight junction protein, is dysregulated in colon cancer and its overexpression in colon cancer cells induced dedifferentiation and increased invasion. However, the molecular mechanism(s) underlying dysregulated claudin-1 expression in colon cancer...

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Bibliographic Details
Main Authors: Krishnan, M, Singh, AB, Smith, JJ, Sharma, A, Chen, X, Eschrich, S, Yeatman, TJ, Beauchamp, RD, Dhawan, P
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388773/
https://ncbi.nlm.nih.gov/pubmed/19881542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.324
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