Claudin-1 Up-regulates the Repressor ZEB-1 to Inhibit E-Cadherin Expression in Colon Cancer Cells

BACKGROUND & AIMS: Expression of the tight junction protein claudin-1 is dysregulated in colon tumors and associates with their progression. Up-regulation of claudin-1 reduces expression of E-cadherin. We investigated the mechanisms by which claudin-1 regulates E-cadherin expression and its effe...

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Main Authors: SINGH, AMAR B., SHARMA, ASHOK, SMITH, J. JOSHUA, KRISHNAN, MOORTHY, CHEN, XI, ESCHRICH, STEVEN, WASHINGTON, MARY K., YEATMAN, TIMOTHY J., BEAUCHAMP, R DANIEL, DHAWAN, PUNITA
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395068/
https://ncbi.nlm.nih.gov/pubmed/21878201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.08.038
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