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Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia
Cannabinoids enhance the function of glycine receptors (GlyRs). However, little is known about the mechanisms and behavioral implication of cannabinoid-GlyR interaction. Using mutagenesis and NMR analysis, we have identified a serine at 296 in the GlyR protein critical for the potentiation of I(Gly)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388539/ https://ncbi.nlm.nih.gov/pubmed/21460829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.552 |
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