The CRKL gene encoding an adaptor protein is amplified, overexpressed, and a possible therapeutic target in gastric cancer

BACKGROUND: Genomic DNA amplification is a genetic factor involved in cancer, and some oncogenes, such as ERBB2, are highly amplified in gastric cancer. We searched for the possible amplification of other genes in gastric cancer. METHODS AND RESULTS: A genome-wide single nucleotide polymorphism micr...

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Detalhes bibliográficos
Main Authors: Natsume, Hiroko, Shinmura, Kazuya, Tao, Hong, Igarashi, Hisaki, Suzuki, Masaya, Nagura, Kiyoko, Goto, Masanori, Yamada, Hidetaka, Maeda, Matsuyoshi, Konno, Hiroyuki, Nakamura, Satoki, Sugimura, Haruhiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388458/
https://ncbi.nlm.nih.gov/pubmed/22591714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-97
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