Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer

The effects of abnormalities in the DNA glycosylases NEIL1, NEIL2, and NEIL3 on human cancer have not been fully elucidated. In this paper, we found that the median somatic total mutation loads and the median somatic single nucleotide mutation loads exhibited significant inverse correlations with th...

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Publicat a:Oxid Med Cell Longev
Autors principals: Shinmura, Kazuya, Kato, Hisami, Kawanishi, Yuichi, Igarashi, Hisaki, Goto, Masanori, Tao, Hong, Inoue, Yusuke, Nakamura, Satoki, Misawa, Kiyoshi, Mineta, Hiroyuki, Sugimura, Haruhiko
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794593/
https://ncbi.nlm.nih.gov/pubmed/27042257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1546392
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