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Reduction of voltage gated sodium channel protein in DRG by vector mediated miRNA reduces pain in rats with painful diabetic neuropathy

BACKGROUND: Painful neuropathy is a common complication of diabetes. Previous studies have identified significant increases in the amount of voltage gated sodium channel isoforms Na(V)1.7 and Na(V)1.3 protein in the dorsal root ganglia (DRG) of rats with streptozotocin (STZ)-induced diabetes. We fou...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chattopadhyay, Munmun, Zhou, Zhigang, Hao, Shuanglin, Mata, Marina, Fink, David J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388457/
https://ncbi.nlm.nih.gov/pubmed/22439790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-17
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